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Catalog No.: A12540

Topoisomerase I inhibitor


9-amino-CPT Chemical Structure

CAS NO. 91421-43-1

9-Aminocamptothecin is a topoisomerase I inhibitor with potent anticancer activity.

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Biological Activity

9-Aminocamptothecin is a topoisomerase I inhibitor with potent anticancer activity.
In vitro DMSO 23 mg/mL (63.3 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.52 mL 137.6 mL 275.2 mL
0.5 mM 5.5 mL 27.52 mL 55.04 mL
1 mM 2.75 mL 13.76 mL 27.52 mL
5 mM 0.55 mL 2.75 mL 5.5 mL

*The above data is based on the productmolecular weight 363.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12540
Actions Inhibitor
CAS No. 91421-43-1
Formula C20H17N3O4
M. Wt 363.37
Purity >98%
Synonyms 9-amino-20(S)-camptothecin
SMILES O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(N)C=CC=C5N=C4C3=C2)=O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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