A-395

Name: A-395
Brand: Adooq Bioscience
SKU: A12999
Rating: 5 (288 reviews)

Catalog No.: A12999

PRC2 antagonist

A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM.

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A-395 2089148-72-9 <p>PRC2 antagonist</p>

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Grouped product items
Size	Price	Stock
1mg	$35.00	In stock
5mg	$80.00	In stock
10mg	$125.00	In stock
25mg	$210.00	In stock
50mg	$390.00	In stock
100mg	$690.00	In stock
*10mM 1mL in DMSO**	$90.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Adooq Products cited in reputable paper

Biological Activity

Description

A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM.

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A12999
Formula	C26H35FN4O2S
Molecular Weight	486.65
CAS Number	2089148-72-9
SMILES	O=S(N1CCN(C2=CC=C([C@H]3CN(C4C(C(F)=CC=C5)=C5CC4)C[C@@H]3N(C)C)C=C2)CC1)(C)=O
Synonyms	A395, A 395
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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