A 803467

Name: A 803467
Brand: Adooq Bioscience
SKU: A11234
Rating: 100 (268 reviews)

Catalog No.: A11234

Sodium channel Blocker

A 803467 Chemical Structure

CAS NO. 944261-79-4

A 803467 is a selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively).

Availability: In stock

Package	Price	Qty
10 mg	$50.00
25 mg	$98.00
50 mg	$150.00
100 mg	$250.00
10mM * 1mL in DMSO	$77.00
Custom Size	Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Bulk Inquiry

Get Free Sample

Price Match

Add to Wishlist

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Biological Activity

A 803467 is a selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively).

Targets

Na(V1.8) channel
8 nM

Solubility *

In vitro (25°C)	DMSO	64 mg/mL (178.87 mM)
	Water	Insoluble
	Ethanol	10 mg/mL (27.95 mM)
In vivo	2% DMSO+corn oil	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.95 mL	139.74 mL	279.49 mL
0.5 mM	5.59 mL	27.95 mL	55.9 mL
1 mM	2.79 mL	13.97 mL	27.95 mL
5 mM	0.56 mL	2.79 mL	5.59 mL

*The above data is based on the productmolecular weight 357.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11234
Actions	Blocker
CAS No.	944261-79-4
Formula	C19H16ClNO4
M. Wt	357.8
Purity	>98%
Synonyms	A-803467, A803467
SMILES	COC1=CC(=CC(=C1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)Cl)OC
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.