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Publications citing Adooq Products
Chemical Information
| Catalog Num | A11234 |
|---|---|
| Actions | Blocker |
| M. Wt | 357.8 |
| Formula | C19H16ClNO4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 944261-79-4 |
| Synonyms | A-803467, A803467 |
| SMILES code | COC1=CC(=CC(=C1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)Cl)OC |
| Chemical Name | 5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furancarboxamide |
Description |
A 803467 is a selective blocker of NaV1.8 channels (IC50 values are 8, 2450, 6740, 7340 and 7380 nM for hNaV1.8, hNaV1.3, hNaV1.7, hNaV1.5 and hNaV1.2 channels respectively). | ||||||||||
Targets |
|
||||||||||
| Solubility (25°C) * | In vitro | DMSO | 72 mg/mL (201.23 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 11 mg/mL (30.74 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.95 mL | 139.74 mL | 279.49mL |
| 0.5 mM | 5.59 mL | 27.95 mL | 55.9 mL |
| 1 mM | 2.79 mL | 13.97 mL | 27.95 mL |
| 5 mM | 0.56 mL | 2.79 mL | 5.59 mL |
*The above data is based on the productmolecular weight 357.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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