A-935142 is a potent activator of the human ether-a-go-go-related gene (hERG, Kv 11.1) channel. This compound modulates hERG current through a multifaceted mechanism, promoting activation, diminishing inactivation, and decelerating deactivation. A-935142 is crucial for studies investigating cardiac repolarization processes and the pharmacological modulation of ion channels associated with arrhythmias.
A-935142 is a potent activator of the human ether-a-go-go-related gene (hERG, Kv 11.1) channel. This compound modulates hERG current through a multifaceted mechanism, promoting activation, diminishing inactivation, and decelerating deactivation. A-935142 is crucial for studies investigating cardiac repolarization processes and the pharmacological modulation of ion channels associated with arrhythmias.
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