A3373 is a novel inhibitor of Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), exhibiting IC50 values of 325 nM and 15.15 μM, respectively. This compound effectively inhibits lipopolysaccharide (LPS)-induced immune responses, making it valuable for research in autoimmune arthritis, bone demineralization, and osteoclastogenesis. Its action on phospholipase pathways underscores its potential for studying related inflammatory and osteological disorders.
A3373 is a novel inhibitor of Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), exhibiting IC50 values of 325 nM and 15.15 μM, respectively. This compound effectively inhibits lipopolysaccharide (LPS)-induced immune responses, making it valuable for research in autoimmune arthritis, bone demineralization, and osteoclastogenesis. Its action on phospholipase pathways underscores its potential for studying related inflammatory and osteological disorders.
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