A3AR agonist 5

Catalog No.: A57996
A3AR Agonist
A3AR Agonist 5 is a potent activator of the A3 adenosine receptor (A3AR), exhibiting EC50 and Ki values of 0.14 nM and 6.36 nM for cAMP and human A3 receptors, respectively. This compound is valuable for research into pain modulation and inflammation, making it a significant tool for studies examining adenosine receptor signaling pathways and their therapeutic implications.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionA3AR Agonist 5 is a potent activator of the A3 adenosine receptor (A3AR), exhibiting EC50 and Ki values of 0.14 nM and 6.36 nM for cAMP and human A3 receptors, respectively. This compound is valuable for research into pain modulation and inflammation, making it a significant tool for studies examining adenosine receptor signaling pathways and their therapeutic implications.
Product Information
Catalog NumA57996
FormulaC18H17ClN6O2
Molecular Weight384.82
CAS Number3032475-38-7
SMILESO[C@@H]1[C@@]2(C3=NC=CN3)[C@]([C@@H](N4C5=C(C6=C(C=C(N6)C)C(Cl)=N5)N=C4)[C@@H]1O)([H])C2
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