Abiraterone Acetate (CB7630)

Catalog No.: A11058

CYP17 inhibitor

Abiraterone Acetate (CB7630)

Abiraterone Acetate (CB7630) Chemical Structure

CAS NO. 154229-18-2

Abiraterone acetate (CB7630) is an orally active acetate ester of the steroidal compound Abiraterone with antiandrogen activity. Abiraterone inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1).

Availability: In stock

Package Price Qty
5 mg
$30.00
10 mg
$50.00
50 mg
$60.00
100 mg
$80.00
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Warning WARNING: Attention California Residents: This product can expose you to chemicals including Abiraterone Acetate (CB7630) , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Abiraterone acetate (CB7630) is an orally active acetate ester of the steroidal compound Abiraterone with antiandrogen activity. Abiraterone inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1).
Targets
CYP17 (Cell-free assay)
72 nM
In vitro (25°C) DMSO Insoluble
Water Insoluble
Ethanol 27 mg/mL
In vivo 5% DMSO+95% Corn oil 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.56 mL 127.78 mL 255.56 mL
0.5 mM 5.11 mL 25.56 mL 51.11 mL
1 mM 2.56 mL 12.78 mL 25.56 mL
5 mM 0.51 mL 2.56 mL 5.11 mL

*The above data is based on the productmolecular weight 391.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11058
Actions Inhibitor
CAS No. 154229-18-2
Formula C26H33NO2
M. Wt 391.3
Purity >98%
Synonyms CB-7630
SMILES CC(=O)O[[email protected]]1CC[[email protected]@]2([[email protected]]3CC[[email protected]]4([[email protected]]([[email protected]@H]3CC=C2C1)CC=C4C5=CN=CC=C5)C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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