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$0.00 Biological Activity
Abiraterone acetate (CB7630) is an orally active acetate ester of the steroidal compound Abiraterone with antiandrogen activity. Abiraterone inhibits 17 α-hydroxylase/C17,20 lyase (CYP17A1).
Targets
| CYP17 (Cell-free assay) | ||||
| 72 nM |
| In vitro (25°C) | DMSO | Insoluble | |
| Water | Insoluble | ||
| Ethanol | 27 mg/mL | ||
| In vivo | 5% DMSO+95% Corn oil | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.56 mL | 127.78 mL | 255.56 mL |
| 0.5 mM | 5.11 mL | 25.56 mL | 51.11 mL |
| 1 mM | 2.56 mL | 12.78 mL | 25.56 mL |
| 5 mM | 0.51 mL | 2.56 mL | 5.11 mL |
*The above data is based on the productmolecular weight 391.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11058 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 154229-18-2 |
| Formula | C26H33NO2 |
| M. Wt | 391.3 |
| Purity | >98% |
| Synonyms | CB-7630 |
| SMILES | CC(=O)O[[email protected]]1CC[[email protected]@]2([[email protected]]3CC[[email protected]]4([[email protected]]([[email protected]@H]3CC=C2C1)CC=C4C5=CN=CC=C5)C)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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