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Publications citing Adooq Products
ABT 492 meglumine (Delafloxacin meglumine) Citations (2)
- Azuma T,et al. Distribution of six anticancer drugs and a variety of other pharmaceuticals, and their sorption onto sediments, in an urban Japanese river, Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 28660504
- Azuma T,et al. Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents, Sci Total Environ, 2016, Apr 1;548-549:189-197 26802347
Chemical Information
| Catalog Num | A15064 |
|---|---|
| Actions | No |
| M. Wt | 635.97 |
| Formula | C25H29ClF3N5O9 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 352458-37-8 |
| Synonyms | ABT492 meglumine, ABT-492 meglumine, Delafloxacin meglumine |
| SMILES code | CNCC(C(C(C(CO)O)O)O)O.C1C(CN1C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4=NC(=C(C=C4F)F)N)F)O |
| Chemical Name | 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid |
Description |
ABT 492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonfermentative, gram-negative organisms. in vitro: | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.72 mL | 78.62 mL | 157.24mL |
| 0.5 mM | 3.14 mL | 15.72 mL | 31.45 mL |
| 1 mM | 1.57 mL | 7.86 mL | 15.72 mL |
| 5 mM | 0.31 mL | 1.57 mL | 3.14 mL |
*The above data is based on the productmolecular weight 635.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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