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AC-4-130 is a novel, potent STAT5 SH2 domain inhibitor, binds to and efficiently blocks STAT5 activation and subsequent transcriptional activity, shows high selectivity for STAT5 over STAT1 and STAT3.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.31 mL | 66.56 mL | 133.12 mL |
| 0.5 mM | 2.66 mL | 13.31 mL | 26.62 mL |
| 1 mM | 1.33 mL | 6.66 mL | 13.31 mL |
| 5 mM | 0.27 mL | 1.33 mL | 2.66 mL |
*The above data is based on the productmolecular weight 751.206. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18314 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1834571-82-2 |
| Formula | C37H36ClF5N2O5S |
| M. Wt | 751.206 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | AC4-130 |
| SMILES | FC1=C(F)C(F)=C(S(=O)(N(CC(N(CC2=CC(C(C)(C)C)=CC(C(C)(C)C)=C2)C3=CC=C(C(O)=O)C=C3)=O)CC4=CC=C(Cl)C=C4)=O)C(F)=C1F |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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