AC-4-130

Catalog No.: A18314

STAT5 SH2 domain inhibitor

AC-4-130

AC-4-130 Chemical Structure

CAS NO. 1834571-82-2

AC-4-130 is a novel, potent STAT5 SH2 domain inhibitor, binds to and efficiently blocks STAT5 activation and subsequent transcriptional activity, shows high selectivity for STAT5 over STAT1 and STAT3.

Availability: In stock

Package Price Qty
5 mg
$550.00
10 mg
$1,000.00
50 mg
$3,500.00
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Biological Activity

AC-4-130 is a novel, potent STAT5 SH2 domain inhibitor, binds to and efficiently blocks STAT5 activation and subsequent transcriptional activity, shows high selectivity for STAT5 over STAT1 and STAT3.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.31 mL 66.56 mL 133.12 mL
0.5 mM 2.66 mL 13.31 mL 26.62 mL
1 mM 1.33 mL 6.66 mL 13.31 mL
5 mM 0.27 mL 1.33 mL 2.66 mL

*The above data is based on the productmolecular weight 751.206. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18314
Actions Inhibitor
CAS No. 1834571-82-2
Formula C37H36ClF5N2O5S
M. Wt 751.206
Solubility DMSO
Purity >98%
Synonyms AC4-130
SMILES FC1=C(F)C(F)=C(S(=O)(N(CC(N(CC2=CC(C(C)(C)C)=CC(C(C)(C)C)=C2)C3=CC=C(C(O)=O)C=C3)=O)CC4=CC=C(Cl)C=C4)=O)C(F)=C1F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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