Ac-RFAAKAA-COOH is a cysteine-containing polypeptide characterized by its reactive lysine residue, making it a valuable substrate for covalent modification and chemical reactivity assays. This compound forms stable covalent adducts with isothiocyanates, which facilitates peptide depletion studies over time. Ac-RFAAKAA-COOH serves as a model peptide in direct peptide reactivity assays and is assessed using fluorescamine-based free amine assays. Its applications extend to research related to allergic contact dermatitis and skin sensitization mechanisms.
Ac-RFAAKAA-COOH is a cysteine-containing polypeptide characterized by its reactive lysine residue, making it a valuable substrate for covalent modification and chemical reactivity assays. This compound forms stable covalent adducts with isothiocyanates, which facilitates peptide depletion studies over time. Ac-RFAAKAA-COOH serves as a model peptide in direct peptide reactivity assays and is assessed using fluorescamine-based free amine assays. Its applications extend to research related to allergic contact dermatitis and skin sensitization mechanisms.
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