Peptides

His-Pro is a dipeptide consisting of histidyl and proline.

Peptide 401, a potent mast cell degranulating factor from bee venom, suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, and 5-HT).

Amyloid beta (Aβ or Abeta) is a peptide of 36-C43 amino acids that is processed from the Amyloid precursor protein. Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. Downregulates bcl-2 and increases the levels of bax. Neurotoxic.

Dynorphin A (1-13) Acetate is a potent, endogenous ??-agonist.

Angiotensin I is formed by the action of renin on angiotensinogen.

LEP (116-130) (mouse) is an adipocyte-derived hormone that acts as a major regulator for food intake and energy homeostasis.

Myelin Basic Protein (87-99) is a self-antigen in multiple sclerosis (MS).

Angiotensin (1-7) is an endogenous peptide fragment that can be produced from Ang I or Ang II via endo- or carboxy-peptidases respectively.

Angiotensin II (Ang II) is an octapeptide hormone that plays a central role in cardiovascular homeostasis.

Angiotensin III is a hexapeptide formed as a result of a cleavage at the N-terminus of Angiotensin II, a key factor in the Renin-Angiotensin-Aldosterone (RAAS) system by angiotensinases located in red blood cells and the vascular beds of most tissues.

Gap 26 is a connexin mimetic peptide, corresponding to residues 63-75 of connexin 43, which is a gap junction blocker.

Gap 27 is a peptide derived from connexin 43 that is a selective gap junction blocker.

Dynamin Inhibitory Peptide is a peptide inhibitor of the GTPase dynamin.

PKA inhibitor fragment (6-22) amide is a synthetic peptide that acts as a protein kinase inhibitor.

Secretin (human),gastrointestinal peptide that stimulates pancreatic and biliary secretion.

Melanocyte stimulating hormone release inhibiting factor is an endogenous peptide fragment derived from cleavage of the hormone oxytocin, but having generally different actions in the body.

PKC (19-36), pseudosubstrate peptide inhibitor of protein kinase C (IC50 = 0.18 uM).

COG 133 is 299 amino acids long and transports lipoproteins, fat-soluble vitamins, and cholesterol into the lymph system and then into the blood.

Angiotensin 1/2 (1-9) is a peptide (ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS) containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.

Anti-Inflammatory Peptide 1, belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I.

Glucagon (19-29) (human) is a potent Ca 2+ /Mg 2+ -ATPase inhibitor.

N/A

Epidermal Growth Factor Receptor Peptide (985-996) exists on the cell surface and is activated by the binding of its specific ligands, including epidermal growth factor and transforming growth factor.

Laminin (925-933) is a peptide derived from residues 925-933 of the laminin B1 chain that binds to the laminin receptor.

Cadherin Peptide, avian, is a class of type-1 transmembrane proteins.

Fas C- Terminal Tripeptide is a tri-peptide with the sequence AC-SER-LEU-VAL-OH.

Myelin Basic Protein (68-82), guinea pig is a peptide.

Protein Kinase C (19-31), this peptide derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, it was used as protein kinase C substrate peptide for testing the protein kinase C activity.

Acetyl Angiotensinogen (1-14),porcine, The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor.

Thrombin Receptor Activator for Peptide 5 (TRAP-5), coagulation factor II (thrombin) receptor is a G protein-coupled receptor involved in the regulation of thrombotic response.

N/A

N/A

N/A

BNP (1-32), human is a brain natriuretic peptide secreted by the human heart in response to cardiac volume or pressure.

Corticotropin Releasing Factor, bovine, neurotransmitter and CRF receptor antagonist.

N/A

Parathyroid hormone (PTH) is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid, which is secreted by the chief cell of the parathyroid glands as a polypeptide containing 84 amino acids.

Peptide YY (PYY) is a short (36-amino acid) peptide released by cells in the ileum and colon in response to feeding. It is also known as peptide tyrosine tyrosine or pancreatic peptide YY3-36.

FLAG tag Peptide is a 8 amino acid peptide with an enterokinase-cleavage site used for the purification of recombinant proteins.

Influenza Hemagglutinin (HA) Peptide is a tag peptide derived from an epitope of the influenza hemagglutinin protein.

Difopein, dimeric version of R18 peptide that binds to 14.3.3 proteins with high affinity.

Bax inhibitor peptide P5, cell-permeable synthetic peptide inhibitor of Bax translocation to mitochondria; designed from Ku70, a protein that is suggested to suppress the mitochondrial translocation of Bax. Inhibits Bax-mediated apoptosis in vitro.

Bax inhibitor peptide V5, cell-permeable synthetic peptide inhibitor of Bax translocation to mitochondria; designed from Ku70, a protein that is suggested to suppress the mitochondrial translocation of Bax. Inhibits Bax-mediated apoptosis in vitro.

Bax inhibitor peptide, negative control, negative control peptide for the Bax inhibitor peptides V5 and P5 , which inhibit Bax translocation to mitochondria and Bax-mediated apoptosis in vitro.

TLQP 21, VGF-derived peptide; spans residues 556-576 of the precursor sequence.

Amyloid b-peptide (42-1) (human), inactive control for Amyloid b (1-42) peptide.

Amyloid b-Peptide (10-20) (human), soluble amyloid b-peptide fragment that is a substrate for gelatinase A/type IV collagenase/MMP-2 and APP secretase; cleaved between Lys16 and Leu17.

Amyloid b-peptide (25-35) (human), fragment of human amyloid beta-peptide, functionally required for the neurotrophic and neurotoxic effects associated with Alzheimer's disease.

Amyloid b-Peptide (12-28) (human), amyloid b-peptide fragment; minimum section required to bind to brain proteins.

Amyloid b-Peptide (1-40) (human) is a peptide processed from the amyloid precursor protein (APP).