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$0.00 - Sumit Bansal, .et al. Inhibition of Human Sulfotransferase 2A1-Catalyzed Sulfonation of Lithocholic Acid, Glycolithocholic Acid, and Taurolithocholic Acid by Selective Estrogen Receptor Modulators and Various Analogs and Metabolites, J Pharmacol Exp Ther, 2019, June, 369 (3) 389-405
- Lirit N. Franks, .et al. Selective Estrogen Receptor Modulators: Cannabinoid Receptor Inverse Agonists with Differential CB1 and CB2 Selectivity, Front Pharmacol, 2016, 7: 503 PMID: 28066250
Biological Activity
acolbifene is a substance being studied in the prevention of breast cancer in women at high risk of breast cancer. Acolbifene hydrochloride binds to estrogen receptors in the body and blocks the effects of estrogen in the breast. It is a type of selective estrogen receptor modulator (SERM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.86 mL | 109.28 mL | 218.55 mL |
| 0.5 mM | 4.37 mL | 21.86 mL | 43.71 mL |
| 1 mM | 2.19 mL | 10.93 mL | 21.86 mL |
| 5 mM | 0.44 mL | 2.19 mL | 4.37 mL |
*The above data is based on the productmolecular weight 457.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12771 |
|---|---|
| Actions | Modulator |
| CAS No. | 182167-02-8 |
| Formula | C29H31NO4 |
| M. Wt | 457.56 |
| Purity | >98% |
| Synonyms | EM652, EM-652, SCH-57068, SCH 57068 |
| SMILES | CC1=C([[email protected]@H](OC2=C1C=CC(=C2)O)C3=CC=C(C=C3)OCCN4CCCCC4)C5=CC=C(C=C5)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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