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Biological Activity
Adarotene belongs to the so-called class of atypical retinoids. The presence of the phenolic hydroxyl group on Adarotene structure allows a rapid O-glucuronidation as a major mechanism of elimination of the drug, favoring a fast excretion of its glucuronide metabolite in the urines.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.7 mL | 133.51 mL | 267.02 mL |
| 0.5 mM | 5.34 mL | 26.7 mL | 53.4 mL |
| 1 mM | 2.67 mL | 13.35 mL | 26.7 mL |
| 5 mM | 0.53 mL | 2.67 mL | 5.34 mL |
*The above data is based on the productmolecular weight 374.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11298 |
|---|---|
| CAS No. | 496868-77-0 |
| Formula | C25H26O3 |
| M. Wt | 374.5 |
| Purity | >98% |
| Synonyms | ST 1926, ST1926 |
| SMILES | C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC=C(C=C5)/C=C/C(=O)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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