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Biological Activity
ADL5859 HCl is a highly potent and selective δ opioid receptor agonist with Ki value to be 0.84 nM and ED50 value to be 20 nM.
Targets
| δ-opioid receptor | μ-opioid receptor | κ-opioid receptor | ||
| 0.8 nM(Ki) | 32 nM(Ki) | 37 nM(Ki) |
| In vitro (25°C) | DMSO | 76 mg/mL (177.17 mM) | |
| Water | 4 mg/mL (9.32 mM) | ||
| Ethanol | 1 mg/mL (2.33 mM) | ||
| In vivo | 0.5% hydroxyethyl cellulose+0.1% Tween 80 | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.31 mL | 116.55 mL | 233.1 mL |
| 0.5 mM | 4.66 mL | 23.31 mL | 46.62 mL |
| 1 mM | 2.33 mL | 11.66 mL | 23.31 mL |
| 5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
*The above data is based on the productmolecular weight 429. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11072 |
|---|---|
| Actions | Agonist |
| CAS No. | 850173-95-4 |
| Formula | C24H28N2O3.HCl |
| M. Wt | 429 |
| Purity | >98% |
| Synonyms | ADL-5859 |
| SMILES | CCN(CC)C(=O)C1=CC=C(C=C1)C2=CC3(CCNCC3)OC4=C2C(=CC=C4)O.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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