ADL5859 is a selective and orally active δ-opioid receptor (DOR) agonist, exhibiting a Ki of 0.84 nM and an EC50 value of 20 nM. In addition, it demonstrates inhibitory activity on the hERG channel with an IC50 of 78 μM. This compound is primarily utilized in pain research, providing insight into opioid receptor mechanisms and potential therapeutic applications.
ADL5859 is a selective and orally active δ-opioid receptor (DOR) agonist, exhibiting a Ki of 0.84 nM and an EC50 value of 20 nM. In addition, it demonstrates inhibitory activity on the hERG channel with an IC50 of 78 μM. This compound is primarily utilized in pain research, providing insight into opioid receptor mechanisms and potential therapeutic applications.
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