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Adriamycin is an anthracycline antibiotic, it works by intercalating DNA, while most serious adverse effect being life-threatening heart damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.
Targets
| Topo II (Tumor cells) | ||||
| In vitro | DMSO | 100 mg/mL (172.41 mM) | |
| Water | 20 mg/mL (34.48 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.24 mL | 86.21 mL | 172.41 mL |
| 0.5 mM | 3.45 mL | 17.24 mL | 34.48 mL |
| 1 mM | 1.72 mL | 8.62 mL | 17.24 mL |
| 5 mM | 0.34 mL | 1.72 mL | 3.45 mL |
*The above data is based on the productmolecular weight 580.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Technical Details
| Catalog Num | A10041 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 580.0 |
| Formula | C27H29NO11.HCl |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 25316-40-9 |
| Synonyms | Doxorubicin |
| SMILES | C[[email protected]]1[[email protected]]([[email protected]](C[[email protected]@H](O1)O[[email protected]]2C[[email protected]@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl |
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