AFD-21 maleate is a selective sodium channel inhibitor exhibiting antiarrhythmic properties. It binds preferentially to sodium channels in their inactive state, demonstrating both use-dependent and voltage-dependent blocking effects. At specific concentrations, AFD-21 maleate can prolong action potential duration and significantly decrease the maximum rise rate of the action potential. This compound is of particular interest in cardiovascular research for its potential applications in arrhythmia management.
AFD-21 maleate is a selective sodium channel inhibitor exhibiting antiarrhythmic properties. It binds preferentially to sodium channels in their inactive state, demonstrating both use-dependent and voltage-dependent blocking effects. At specific concentrations, AFD-21 maleate can prolong action potential duration and significantly decrease the maximum rise rate of the action potential. This compound is of particular interest in cardiovascular research for its potential applications in arrhythmia management.
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