AG-13958

Catalog No.: A21175

VEGFR inhibitor

AG-13958

AG-13958 Chemical Structure

CAS NO. 319460-94-1

AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD).

Availability: In stock

Package Price Qty
5 mg
$383.00
10 mg
$659.00
50 mg
$1,955.00
100 mg
$3,910.00
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Biological Activity

AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD).
In vitro DMSO 91 mg/mL (194.64 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.39 mL 106.95 mL 213.9 mL
0.5 mM 4.28 mL 21.39 mL 42.78 mL
1 mM 2.14 mL 10.7 mL 21.39 mL
5 mM 0.43 mL 2.14 mL 4.28 mL

*The above data is based on the productmolecular weight 467.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21175
Actions Inhibitor
CAS No. 319460-94-1
Formula C26H22FN7O
M. Wt 467.5
Solubility DMSO
Purity >98%
Synonyms AG 13958, AG13958, AG-013958, AG 013958, AG013958
SMILES O=C(C1=CC(C)=NN1C)NC2=CC(NC3=CC4=C(C=C3)C(/C=C/C5=NC=CC=C5)=NN4)=CC=C2F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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