AG-17

Catalog No.: A11949
EGFR inhibitor
AG-17 is an inhibitor of EGF receptor kinase with an IC50 value of 460 μM in the human epidermoid carcinoma cell line A431.
Grouped product items
Product Name Price Stock Qty
AG-17 50mg
Special Price $48.00 Regular Price $60.00
In stock
AG-17 100mg
Special Price $88.00 Regular Price $110.00
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AG-17 200mg
Special Price $160.00 Regular Price $200.00
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AG-17 500mg
Special Price $400.00 Regular Price $500.00
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AG-17 10mM * 1mL in DMSO
Special Price $40.00 Regular Price $50.00
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Biological Activity
Discription AG-17 is an inhibitor of EGF receptor kinase with an IC50 value of 460 μM in the human epidermoid carcinoma cell line A431.
Targets
Target Value
Product Information
Catalog Num A11949
Formula C18H22N2O
Molecular Weight 282.4
CAS Number 10537-47-0
SMILES CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C#N
Synonyms NSC 242557, RG-50872, GCP 5126, SF 6847, Tyrphostin AG-17, Malonoben, Tyrphostin 9
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 51 mg/mL (180.6 mM)
Water Insoluble
Ethanol 51 mg/mL (180.6 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.41 mL 177.05 mL 354.11 mL
0.5 mM 7.08 mL 35.41 mL 70.82 mL
1 mM 3.54 mL 17.71 mL 35.41 mL
5 mM 0.71 mL 3.54 mL 7.08 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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