AG-18 (Tyrphostin 23)

Name: AG-18 (Tyrphostin 23)
Brand: Adooq Bioscience
SKU: A15940
Rating: 100 (268 reviews)

Catalog No.: A15940

EGFR Inhibitor

AG-18 (Tyrphostin 23) Chemical Structure

CAS NO. 118409-57-7

AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 ,M in the human epidermoid carcinoma cell line A431.

Availability: In stock

Package	Price	Qty
25 mg	$110.00
50 mg	$200.00
100 mg	$350.00
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Biological Activity

AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 ,M in the human epidermoid carcinoma cell line A431.

Targets

EGFR
35 μM

Solubility *

In vitro	DMSO	34 mg/mL (182.63 mM)
	Water	Insoluble
	Ethanol	34 mg/mL (182.63 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	53.71 mL	268.57 mL	537.14 mL
0.5 mM	10.74 mL	53.71 mL	107.43 mL
1 mM	5.37 mL	26.86 mL	53.71 mL
5 mM	1.07 mL	5.37 mL	10.74 mL

*The above data is based on the productmolecular weight 186.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A15940
Actions	Inhibitor
CAS No.	118409-57-7
Formula	C10H6N2O2
M. Wt	186.17
Purity	>98%
Synonyms	RG-50810, RG-50858, TX 825, Tyrphostin 23, Tyrphostin A23, Tyrphostin AG-18
SMILES	N#C/C(C#N)=C/C1=CC=C(O)C(O)=C1
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.