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AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 ,M in the human epidermoid carcinoma cell line A431.
Targets
| EGFR | ||||
| 35 μM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 53.71 mL | 268.57 mL | 537.14 mL |
| 0.5 mM | 10.74 mL | 53.71 mL | 107.43 mL |
| 1 mM | 5.37 mL | 26.86 mL | 53.71 mL |
| 5 mM | 1.07 mL | 5.37 mL | 10.74 mL |
*The above data is based on the productmolecular weight 186.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A15940 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 186.17 |
| Formula | C10H6N2O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 118409-57-7 |
| Synonyms | RG-50810, RG-50858, TX 825, Tyrphostin 23, Tyrphostin A23, Tyrphostin AG-18 |
| SMILES | N#C/C(C#N)=C/C1=CC=C(O)C(O)=C1 |
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