AG-18 (Tyrphostin 23)

Catalog No.: A15940

EGFR Inhibitor

AG-18 (Tyrphostin 23)

AG-18 (Tyrphostin 23) Chemical Structure

CAS NO. 118409-57-7

AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 ,M in the human epidermoid carcinoma cell line A431.

Availability: In stock

Package Price Qty
25 mg
$110.00
50 mg
$200.00
100 mg
$350.00
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Biological Activity

AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 ,M in the human epidermoid carcinoma cell line A431.
Targets
EGFR
35 μM
In vitro DMSO 34 mg/mL (182.63 mM)
Water Insoluble
Ethanol 34 mg/mL (182.63 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 53.71 mL 268.57 mL 537.14 mL
0.5 mM 10.74 mL 53.71 mL 107.43 mL
1 mM 5.37 mL 26.86 mL 53.71 mL
5 mM 1.07 mL 5.37 mL 10.74 mL

*The above data is based on the productmolecular weight 186.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15940
Actions Inhibitor
CAS No. 118409-57-7
Formula C10H6N2O2
M. Wt 186.17
Purity >98%
Synonyms RG-50810, RG-50858, TX 825, Tyrphostin 23, Tyrphostin A23, Tyrphostin AG-18
SMILES N#C/C(C#N)=C/C1=CC=C(O)C(O)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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