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AGN 205728

RARγ antagonist

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Catalog No. A16296

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
AGN 205728 5mg A16296-5
AGN 205728 10mg A16296-10
AGN 205728 50mg A16296-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

AGN 205728 is a potent and selective RARγ antagonist with Ki/IC95 values of 3 nM/ 0.6 nM; no inhibiton on RARα and RARβ.

AGN 205728

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Chemical Information

Catalog Num A16296
Actions Antagonist
M. Wt 437.53
Formula C29H27NO3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 859498-05-8
Synonyms AGN205728, AGN-205728
SMILES CC1=CC=C(C=C1)C2=CCC(C)(C)C3=C2C=CC(=C3)/C(=N/O)/C=C/C4=CC=C(C=C4)C(=O)O

Biological Activity

AGN 205728 is a potent and selective RARγ antagonist with Ki/IC95 values of 3 nM/ 0.6 nM; no inhibiton on RARα and RARβ.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.86 mL 114.28 mL 228.56mL
0.5 mM 4.57 mL 22.86 mL 45.71 mL
1 mM 2.29 mL 11.43 mL 22.86 mL
5 mM 0.46 mL 2.29 mL 4.57 mL

*The above data is based on the productmolecular weight 437.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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