AGN194204 is a selective retinoid X receptor (RXR) agonist with high affinity, exhibiting Kd values of 0.4 nM, 3.6 nM, and 3.8 nM for RXRα, RXRβ, and RXRγ, respectively, and EC50 values of 0.2 nM, 0.8 nM, and 0.08 nM. This compound is devoid of activity against retinoic acid receptors (RAR). AGN194204 demonstrates significant anti-inflammatory and anticarcinogenic properties, making it a valuable tool for research in inflammation and cancer biology.
AGN194204 is a selective retinoid X receptor (RXR) agonist with high affinity, exhibiting Kd values of 0.4 nM, 3.6 nM, and 3.8 nM for RXRα, RXRβ, and RXRγ, respectively, and EC50 values of 0.2 nM, 0.8 nM, and 0.08 nM. This compound is devoid of activity against retinoic acid receptors (RAR). AGN194204 demonstrates significant anti-inflammatory and anticarcinogenic properties, making it a valuable tool for research in inflammation and cancer biology.
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