AH3960 is a selective agonist of the parathyroid hormone receptor 1 (PTHR1). It has demonstrated significant biological activity through its ability to activate PTHR1, contributing to studies in bone metabolism and calcium homeostasis. Additionally, AH3960 exhibits inhibitory effects on androgen receptors, specifically targeting both wild-type and the T877 mutant variant, with an IC50 value of 0.82 μM. This dual functionality makes AH3960 a valuable tool for research in endocrine signaling and related pathways.
AH3960 is a selective agonist of the parathyroid hormone receptor 1 (PTHR1). It has demonstrated significant biological activity through its ability to activate PTHR1, contributing to studies in bone metabolism and calcium homeostasis. Additionally, AH3960 exhibits inhibitory effects on androgen receptors, specifically targeting both wild-type and the T877 mutant variant, with an IC50 value of 0.82 μM. This dual functionality makes AH3960 a valuable tool for research in endocrine signaling and related pathways.
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