AHPC-PEG6-CH2COOH

Catalog No.: A80101
E3 Ligase Ligand-Linker Conjugate
AHPC-PEG6-CH2COOH is a conjugate designed to facilitate interactions with E3 ligases, featuring a von Hippel-Lindau (VHL) ligand linked through a 6-unit polyethylene glycol (PEG) chain. This reagent serves as a valuable tool in the synthesis of PROTAC CMP98, enabling targeted protein degradation applications in chemical biology research. Its unique structure allows for improved solubility and bioavailability, making it suitable for various studies involving targeted protein modulation.
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50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAHPC-PEG6-CH2COOH is a conjugate designed to facilitate interactions with E3 ligases, featuring a von Hippel-Lindau (VHL) ligand linked through a 6-unit polyethylene glycol (PEG) chain. This reagent serves as a valuable tool in the synthesis of PROTAC CMP98, enabling targeted protein degradation applications in chemical biology research. Its unique structure allows for improved solubility and bioavailability, making it suitable for various studies involving targeted protein modulation.
Product Information
Catalog NumA80101
FormulaC36H54N4O12S
Molecular Weight766.90
CAS Number2361117-11-3
SMILESO=C(O)COCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N(C[C@H]1O)[C@@H](C1)C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

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