αLβ2 integrin-IN-1

Catalog No.: A57501
αLβ2 Integrin Inhibitor
αLβ2 integrin-IN-1 is an inhibitor of the αLβ2 integrin, designed to obstruct αLβ2 integrin-mediated cell adhesion. This compound is valuable for investigating the role of αLβ2 integrin in various inflammatory conditions and can aid in exploring therapeutic interventions for diseases characterized by aberrant cell adhesion and migration. Its application can enhance understanding of the molecular mechanisms underlying inflammatory responses.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionαLβ2 integrin-IN-1 is an inhibitor of the αLβ2 integrin, designed to obstruct αLβ2 integrin-mediated cell adhesion. This compound is valuable for investigating the role of αLβ2 integrin in various inflammatory conditions and can aid in exploring therapeutic interventions for diseases characterized by aberrant cell adhesion and migration. Its application can enhance understanding of the molecular mechanisms underlying inflammatory responses.
Product Information
Catalog NumA57501
FormulaC22H18Cl2N4O3
Molecular Weight457.31
CAS Number579526-88-8
SMILESO=C(N(C1=CC(Cl)=CC(Cl)=C1)C2=O)N(C[C@H](C3)NC(C)=O)[C@]23CC4=CC=C(C=C4)C#N
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