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Alcaftadine

Catalog No.: A16393

H1 histamine receptor antagonist

Alcaftadine

Alcaftadine Chemical Structure

CAS NO. 147084-10-4

Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.

Availability: In stock

Package Price Qty
10 mg
$40.00
25 mg
$80.00
100 mg
$220.00
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Biological Activity

Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.
In vitro DMSO 26 mg/mL (84.57 mM)
Water Insoluble
Ethanol 57 mg/mL (185.43 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.53 mL 162.66 mL 325.32 mL
0.5 mM 6.51 mL 32.53 mL 65.06 mL
1 mM 3.25 mL 16.27 mL 32.53 mL
5 mM 0.65 mL 3.25 mL 6.51 mL

*The above data is based on the productmolecular weight 307.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16393
Actions Antagonist
CAS No. 147084-10-4
Formula C19H21N3O
M. Wt 307.39
Purity >98%
Synonyms R89674, R 89674, R-89674
SMILES CN1CC/C(CC1)=C2C3=CC=CC=C3CCN4C(C=O)=CN=C/24
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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