Almorexant HCl

Catalog No.: A14286
OX1/OX2 Antagonist
Almorexant HCl is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor 3.
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Product Name Price Stock Qty
Almorexant HCl 5mg
Special Price $96.00 Regular Price $120.00
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Almorexant HCl 10mg
Special Price $160.00 Regular Price $200.00
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Almorexant HCl 25mg
Special Price $360.00 Regular Price $450.00
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Almorexant HCl 10mM * 1mL in DMSO
Special Price $116.00 Regular Price $145.00
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Adooq Products cited in reputable paper
Adooq's Almorexant HCl has been cited by 1 publications
  • Ryan J Keenan, .et al. , Br J Pharmacol, 2022, Jul;179(13):3403-3417 PMID: 35112344
  • Biological Activity
    Discription Almorexant HCl is an orally active, dual orexin receptor antagonist with IC50 of 6.6 nM and 3.4 nM for OX1 and OX2 receptor 3.
    Targets
    Target Value
    Product Information
    Catalog Num A14286
    Formula C29H32ClF3N2O3
    Molecular Weight 549.02
    CAS Number 913358-93-7
    SMILES CNC(=O)[C@@H](C1=CC=CC=C1)N2CCC3=CC(=C(C=C3[C@@H]2CCC4=CC=C(C=C4)C(F)(F)F)OC)OC.Cl
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 62 mg/mL (112.93 mM)
    Water Insoluble
    Ethanol 44 mg/mL (80.14 mM)
    In vivo 2% DMSO+25% ??-cyclodextrin in saline 8 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.21 mL 91.07 mL 182.14 mL
    0.5 mM 3.64 mL 18.21 mL 36.43 mL
    1 mM 1.82 mL 9.11 mL 18.21 mL
    5 mM 0.36 mL 1.82 mL 3.64 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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