Catalog No.: A12779

neutrophil elastase inhibitor


Alvelestat Chemical Structure

CAS NO. 848141-11-7

Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (NE).

Availability: In stock

Package Price Qty
5 mg

Regular Price: $120.00

Special Price $108.00

10 mg

Regular Price: $190.00

Special Price $171.00

25 mg

Regular Price: $350.00

Special Price $315.00

10mM * 1mL in DMSO

Regular Price: $223.00

Special Price $200.70

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (NE).
neutrophil elastase neutrophil elastase
9.4 nM(Ki)12 nM
In vitro DMSO 100 mg/mL (183.3 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.33 mL 91.66 mL 183.32 mL
0.5 mM 3.67 mL 18.33 mL 36.66 mL
1 mM 1.83 mL 9.17 mL 18.33 mL
5 mM 0.37 mL 1.83 mL 3.67 mL

*The above data is based on the productmolecular weight 545.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12779
Actions Inhibitor
M. Wt 545.5
Formula C25H22F3N5O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 848141-11-7
Synonyms AZD9668,AZD 9668,AZD-9668

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