Alvimopan dihydrate

Catalog No.: A14991

µ-opioid receptor agonist

Alvimopan dihydrate

Alvimopan dihydrate Chemical Structure

CAS NO. 170098-38-1

Alvimopan dihydrate(LY 246736, ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.

Availability: In stock

Package Price Qty
5 mg
$100.00
10 mg
$145.00
50 mg
$435.00
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Biological Activity

Alvimopan dihydrate(LY 246736, ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.
In vitro DMSO 79 mg/mL (171.52 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.71 mL 108.56 mL 217.13 mL
0.5 mM 4.34 mL 21.71 mL 43.43 mL
1 mM 2.17 mL 10.86 mL 21.71 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 460.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14991
Actions Agonist
CAS No. 170098-38-1
Formula C25H36N2O6
M. Wt 460.56
Purity >98%
Synonyms LY 246736 dihydrate, ADL 8-2698 dihydrate
SMILES CC1CN(CCC1(C)C2=CC(=CC=C2)O)CC(CC3=CC=CC=C3)C(=O)NCC(=O)O.O.O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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