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AM-5262

Catalog No.: A60356
GPR40 Full Agonist
AM-5262 is a full agonist of the GPR40 receptor, exhibiting an EC50 value of 0.081 μM. This compound is primarily utilized in research focused on type II diabetes and its associated metabolic pathways, providing valuable insights into glucose regulation and insulin secretion mechanisms.
AM-5262 1222088-90-5 GPR40 Full Agonist
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAM-5262 is a full agonist of the GPR40 receptor, exhibiting an EC50 value of 0.081 μM. This compound is primarily utilized in research focused on type II diabetes and its associated metabolic pathways, providing valuable insights into glucose regulation and insulin secretion mechanisms.
Product Information
Catalog NumA60356
FormulaC33H35FO4
Molecular Weight514.63
CAS Number1222088-90-5
SMILESCOC1=CC=C(F)C(C2=C([C@@H]3CCCC3(C)C)C=C(COC4=CC=C(CC[C@]56C[C@]6(C(O)=O)[H])C5=C4)C=C2)=C1
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Endocrinology-Hormones > GPR