Biological Activity
AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 14.43 mL | 72.16 mL | 144.33 mL |
0.5 mM | 2.89 mL | 14.43 mL | 28.87 mL |
1 mM | 1.44 mL | 7.22 mL | 14.43 mL |
5 mM | 0.29 mL | 1.44 mL | 2.89 mL |
*The above data is based on the productmolecular weight 692.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A14994 |
---|---|
Actions | Inhibitor |
M. Wt | 692.87 |
Formula | C40H44N4O5S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1206880-66-1 |
SMILES | CC(=O)N1C(CC2=CC=CC=C21)COC3=CC4=C(C=C3)N(C(=C4SC(C)(C)C)CC(C)(C)C(=O)O)CC5=CC=C(C=C5)C6=NC=C(C=N6)OC |
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