Amg-1

Catalog No.: A75713
IDO1 Inhibitor
Amg-1 is a potent and reversible inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with an IC50 value of 3.0 μM. It demonstrates significant selectivity, with over 80-fold greater inhibition of IDO1 compared to IDO2 and over 20-fold selectivity against TDO. This compound is valuable for research in cancer, hypotension, and neurological disorders, facilitating the exploration of therapeutic strategies targeting immune regulation and metabolism.
Grouped product items
Size Price Stock Qty
1mg
$115.00
In stock
5mg
$300.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAmg-1 is a potent and reversible inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), with an IC50 value of 3.0 μM. It demonstrates significant selectivity, with over 80-fold greater inhibition of IDO1 compared to IDO2 and over 20-fold selectivity against TDO. This compound is valuable for research in cancer, hypotension, and neurological disorders, facilitating the exploration of therapeutic strategies targeting immune regulation and metabolism.
Product Information
Catalog NumA75713
FormulaC20H16N4O3S2
Molecular Weight424.50
CAS Number496023-55-3
SMILESO=C(NC1=CC=C(OCO2)C2=C1)CSC3=NN=C4N3C(C5=CC=C(C)C=C5)=CS4
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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