Signaling Pathway
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| Discription | AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity. | ||
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| Targets |
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| Catalog Num | A19021 |
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| Formula | C30H30F2N6O3 |
| Molecular Weight | 560.59 |
| CAS Number | 2296729-00-3 |
| SMILES | O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C(C5=C(O)C=CC=C5F)=N4)=O)CC1 |
| Synonyms | AMG 510, AMG510, Sotorasib |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 90 mg/mL (160.54 mM) | |
| Water | Insoluble | ||
| Ethanol | 90 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.84 mL | 89.19 mL | 178.38 mL |
| 0.5 mM | 3.57 mL | 17.84 mL | 35.68 mL |
| 1 mM | 1.78 mL | 8.92 mL | 17.84 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.57 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
