AMG-510 (Sotorasib)

Catalog No.: A19021
KRAS G12C covalent inhibitor
AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.
Grouped product items
Product Name Price Stock Qty
AMG-510 5mg
In stock
AMG-510 10mg
In stock

Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.
Target Value
Chemical Information
Catalog Num A19021
Formula C30H30F2N6O3
Molecular Weight 560.59
CAS Number 2296729-00-3
Synonyms AMG 510, AMG510, Sotorasib

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro DMSO 90 mg/mL (160.54 mM)
Water Insoluble
Ethanol 90 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.84 mL 89.19 mL 178.38 mL
0.5 mM 3.57 mL 17.84 mL 35.68 mL
1 mM 1.78 mL 8.92 mL 17.84 mL
5 mM 0.36 mL 1.78 mL 3.57 mL
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