Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order

AMG-510 (Sotorasib)

Catalog No.: A19021

KRAS G12C covalent inhibitor

AMG-510 (Sotorasib)

AMG-510 (Sotorasib) Chemical Structure

CAS NO. 2296729-00-3

AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$160.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

AMG-510 is a potent, orally bioavailable, and selective KRAS G12C covalent inhibitor with anti-tumor activity.
In vitro DMSO 90 mg/mL (160.54 mM)
Water Insoluble
Ethanol 90 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.84 mL 89.19 mL 178.38 mL
0.5 mM 3.57 mL 17.84 mL 35.68 mL
1 mM 1.78 mL 8.92 mL 17.84 mL
5 mM 0.36 mL 1.78 mL 3.57 mL

*The above data is based on the productmolecular weight 560.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19021
Actions Inhibitor
CAS No. 2296729-00-3
Formula C30H30F2N6O3
M. Wt 560.59
Purity >98%
Synonyms AMG 510, AMG510, Sotorasib
SMILES O=C(C=C)N1C[[email protected]](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C(C5=C(O)C=CC=C5F)=N4)=O)CC1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy AMG-510 (Sotorasib) | AMG-510 (Sotorasib) Supplier | purchase | cost | manufacturer | order | distributor | buy 2296729-00-3| 2296729-00-3 Supplier | purchase 2296729-00-3 | 2296729-00-3 cost | 2296729-00-3 manufacturer | order 2296729-00-3 | 2296729-00-3 distributor
Rewards