AMG 579

Catalog No.: A21478

PDE10A inhibitor

AMG 579

AMG 579 Chemical Structure

CAS NO. 1227067-61-9

AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM.

Availability: In stock

Package Price Qty
5 mg
$158.00
10 mg
$271.00
50 mg
$805.00
100 mg
$1,610.00
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Biological Activity

AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.26 mL 226.51 mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21478
Actions Inhibitor
M. Wt 441.48
Formula C25H23N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1227067-61-9
Synonyms AMG-579; AMG579
SMILES CC(N1CCC(C2=NC=CN=C2OC3=CC=C(C(C4=NC5=CC=CC=C5N4)=O)C=C3)CC1)=O

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