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- Veronica Rendo, .et al. Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy, Nat Commun, 2020, 11: 1308 PMID: 32161261
Biological Activity
Amonafide is a DNA intercalator and topoisomerase II inhibitor for the treatment of neoplastic diseases, one of Antitumor agent.
Targets
Topo II | ||||
In vitro | DMSO | 51 mg/mL (179.99 mM) | |
Water | Insoluble | ||
Ethanol | 4 mg/mL (14.11 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 35.3 mL | 176.49 mL | 352.98 mL |
0.5 mM | 7.06 mL | 35.3 mL | 70.6 mL |
1 mM | 3.53 mL | 17.65 mL | 35.3 mL |
5 mM | 0.71 mL | 3.53 mL | 7.06 mL |
*The above data is based on the productmolecular weight 283.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10071 |
---|---|
Actions | Inhibitor |
CAS No. | 69408-81-7 |
Formula | C16H17N3O2 |
M. Wt | 283.3 |
Purity | >98% |
Synonyms | AS1413, Xanafide, Quinamed |
SMILES | CN(C)CCN1C(=O)C2=CC=CC3=CC(=CC(=C32)C1=O)N |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
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