Amyloid β-Protein (1-46)

Catalog No.: A78378
Aβ Fragment
Amyloid β-Protein (1-46) is a fragment of the amyloid precursor protein that primarily targets amyloid aggregation processes. This peptide is crucial for studying the formation and deposition of amyloid plaques, which are characteristic of Alzheimer's disease pathology. It serves as an important tool for research applications aimed at understanding neurodegenerative mechanisms and testing potential therapeutic agents.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAmyloid β-Protein (1-46) is a fragment of the amyloid precursor protein that primarily targets amyloid aggregation processes. This peptide is crucial for studying the formation and deposition of amyloid plaques, which are characteristic of Alzheimer's disease pathology. It serves as an important tool for research applications aimed at understanding neurodegenerative mechanisms and testing potential therapeutic agents.
Product Information
Catalog NumA78378
FormulaC223H347N59O65S
Molecular Weight4926.56
CAS Number285554-31-6
SequenceAsp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Ile-Val
Sequence shorteningDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIV
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