Amyloid β-Protein (1-6)

Catalog No.: A78438
Aβ Fragment
Amyloid β-Protein (1-6) is an Aβ fragment that plays a critical role in Alzheimer's disease research. This peptide has been shown to aggregate and form fibrils, contributing to plaque formation in the brain, which is a hallmark of neurodegenerative disorders. It serves as an important tool for studying amyloid pathology, understanding protein misfolding, and exploring potential therapeutic targets in Alzheimer's disease and related conditions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAmyloid β-Protein (1-6) is an Aβ fragment that plays a critical role in Alzheimer's disease research. This peptide has been shown to aggregate and form fibrils, contributing to plaque formation in the brain, which is a hallmark of neurodegenerative disorders. It serves as an important tool for studying amyloid pathology, understanding protein misfolding, and exploring potential therapeutic targets in Alzheimer's disease and related conditions.
Product Information
Catalog NumA78438
FormulaC33H47N11O11
Molecular Weight773.79
CAS Number214550-64-8
SequenceAsp-Ala-Glu-Phe-Arg-His
Sequence shorteningDAEFRH
SMILES[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)C)=O)CCC(O)=O)=O)C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(O)=O)=O)CCCNC(=N)N)=O
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