Amyloid β-Protein (4-42)

Catalog No.: A78327
Aβ Fragment
Amyloid β-Protein (4-42) is a peptide fragment of the amyloid β-protein that is implicated in the pathogenesis of Alzheimer's disease. This Aβ fragment plays a critical role in the aggregation process that forms amyloid plaques, influencing neurotoxicity and synaptic dysfunction. It is commonly used in research focused on neurodegenerative diseases, enabling studies on amyloid aggregation, cell signaling pathways, and potential therapeutic approaches for Alzheimer's disease.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAmyloid β-Protein (4-42) is a peptide fragment of the amyloid β-protein that is implicated in the pathogenesis of Alzheimer's disease. This Aβ fragment plays a critical role in the aggregation process that forms amyloid plaques, influencing neurotoxicity and synaptic dysfunction. It is commonly used in research focused on neurodegenerative diseases, enabling studies on amyloid aggregation, cell signaling pathways, and potential therapeutic approaches for Alzheimer's disease.
Product Information
Catalog NumA78327
FormulaC191H294N52O53S
Molecular Weight4198.76
CAS Number157884-72-5
SequencePhe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala
Sequence shorteningFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
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