Androgen receptor antagonist 4 is a potent antagonist of the androgen receptor (AR) with an IC50 of 0.15 μM. This compound effectively inhibits AR transcriptional activity, suppresses downstream target gene expression of AR, and prevents dihydrotestosterone (DHT)-induced AR nuclear translocation. It demonstrates promising anticancer properties, making it a valuable tool for studies related to androgen receptor signaling and its implications in cancer research.
Androgen receptor antagonist 4 is a potent antagonist of the androgen receptor (AR) with an IC50 of 0.15 μM. This compound effectively inhibits AR transcriptional activity, suppresses downstream target gene expression of AR, and prevents dihydrotestosterone (DHT)-induced AR nuclear translocation. It demonstrates promising anticancer properties, making it a valuable tool for studies related to androgen receptor signaling and its implications in cancer research.
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