Androgen Receptor Antagonist 5 is a potent inhibitor of the androgen receptor (AR) with an IC50 value of 6.17 μM. This compound effectively hinders AR nuclear translocation, lowering nuclear AR levels and disrupting AR-mediated gene regulation. It demonstrates antiproliferative effects against LNCaP cells and exhibits antitumor activity in LNCaP xenograft mouse models. Androgen Receptor Antagonist 5 is suitable for research applications focused on prostate cancer.
Androgen Receptor Antagonist 5 is a potent inhibitor of the androgen receptor (AR) with an IC50 value of 6.17 μM. This compound effectively hinders AR nuclear translocation, lowering nuclear AR levels and disrupting AR-mediated gene regulation. It demonstrates antiproliferative effects against LNCaP cells and exhibits antitumor activity in LNCaP xenograft mouse models. Androgen Receptor Antagonist 5 is suitable for research applications focused on prostate cancer.
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