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Angexostat

Catalog No.: A78162
Xanthine Oxidase Inhibitor
Angexostat is a potent xanthine oxidase inhibitor, effectively blocking its enzymatic activity. With demonstrated high permeability, Angexostat inhibits CYP2C9 with an IC50 of 18.1 μM. This compound is valuable in research focused on xanthine oxidase-related conditions, including hyperuricemia and gout, providing insights into potential therapeutic strategies.
Angexostat 2640653-91-2 Xanthine Oxidase Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAngexostat is a potent xanthine oxidase inhibitor, effectively blocking its enzymatic activity. With demonstrated high permeability, Angexostat inhibits CYP2C9 with an IC50 of 18.1 μM. This compound is valuable in research focused on xanthine oxidase-related conditions, including hyperuricemia and gout, providing insights into potential therapeutic strategies.
Product Information
Catalog NumA78162
FormulaC16H11F2NO3S
Molecular Weight335.33
CAS Number2640653-91-2
SMILESN#CC1=C(CCC(F)(C2)F)C2=C(C3=CC(O)=C(C(O)=O)C=C3)S1
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Metabolism > Xanthine Oxidase