ADC Linker

PTAD-PEG4-alkyne is a cleavable linker designed for use in antibody-drug conjugate (ADC) synthesis. This 4-unit polyethylene glycol (PEG) linker features an alkyne functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing compounds. Its unique properties facilitate the targeted delivery of therapeutic agents, making it a valuable tool in the development of ADCs for research applications in cancer therapeutics and other fields.

INX-SM-3 is a specialized linker designed for antibody-drug conjugates (ADCs) that incorporates glucocorticosteroid functionality. This compound enables precise delivery of therapeutic agents, enhancing the efficacy of ADCs by leveraging the anti-inflammatory properties of glucocorticosteroids. Its unique structure allows for improved stability and bioactivity, making it suitable for research applications in targeted cancer therapy and immunology studies.

P5(PEG24)-OSu is a polyethylene glycol (PEG) linker designed for antibody-drug conjugate (ADC) applications. This reagent facilitates the synthesis of PROTAC molecules, promoting targeted protein degradation. Its PEGylated structure enhances solubility and improves pharmacokinetic properties, making it a valuable tool in therapeutic research and development focused on precision medicine.

Tr-PEG4-OH is a non-cleavable four-unit polyethylene glycol (PEG) linker designed for use in antibody-drug conjugates (ADCs). Its stable structure facilitates the conjugation of cytotoxic agents to antibodies, enhancing the therapeutic efficacy while minimizing off-target effects. This linker is ideal for research applications involving ADC development and optimization for targeted cancer therapies.

Fmoc-NH-PEG6-alcohol is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This reagent plays a crucial role in enhancing the efficacy and specificity of ADCs by facilitating the controlled release of cytotoxic agents upon internalization. Its structure promotes solubility and stability, making it suitable for various research applications, including cancer therapeutics and targeted drug delivery studies.