Anticancer agent 135 is a potent androgen receptor (AR) antagonist that effectively inhibits AR nuclear translocation and AR/AR-V7 heterodimerization. This compound subsequently disrupts downstream gene transcription, making it a valuable tool in prostate cancer research. Its robust efficacy has been demonstrated in prostate cancer xenograft models, highlighting its potential for therapeutic development in androgen-related malignancies.
Anticancer agent 135 is a potent androgen receptor (AR) antagonist that effectively inhibits AR nuclear translocation and AR/AR-V7 heterodimerization. This compound subsequently disrupts downstream gene transcription, making it a valuable tool in prostate cancer research. Its robust efficacy has been demonstrated in prostate cancer xenograft models, highlighting its potential for therapeutic development in androgen-related malignancies.
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