Anticancer agent 217 is a Camptothecin derivative targeting topoisomerase I, a crucial enzyme involved in DNA replication and repair. It demonstrates potent antitumor activity, with IC50 values of 6.2 nM in MCF-7 cells and 7.1 nM in MDA-MB-231 cells. This compound is suitable for research applications in cancer biology, particularly for studying the mechanisms of tumor cell proliferation and apoptosis.
Anticancer agent 217 is a Camptothecin derivative targeting topoisomerase I, a crucial enzyme involved in DNA replication and repair. It demonstrates potent antitumor activity, with IC50 values of 6.2 nM in MCF-7 cells and 7.1 nM in MDA-MB-231 cells. This compound is suitable for research applications in cancer biology, particularly for studying the mechanisms of tumor cell proliferation and apoptosis.
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