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AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 6.74 mL | 33.72 mL | 67.44 mL |
| 0.5 mM | 1.35 mL | 6.74 mL | 13.49 mL |
| 1 mM | 0.67 mL | 3.37 mL | 6.74 mL |
| 5 mM | 0.13 mL | 0.67 mL | 1.35 mL |
*The above data is based on the productmolecular weight 1482.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21127 |
|---|---|
| CAS No. | 195514-80-8 |
| Formula | C82H107N5O20 |
| M. Wt | 1482.75 |
| Purity | >98% |
| Synonyms | B/B Homodimerizer, AP 20187, AP-20187 |
| SMILES | COC1=C(OC)C=C(CC[[email protected]](C2=CC=CC(OCC(NCC(CN(C)C)CNC(COC3=CC=CC([[email protected]](OC([[email protected]]4N(C([[email protected]@H](CC)C5=CC(OC)=C(OC)C(OC)=C5)=O)CCCC4)=O)CCC6=CC(OC)=C(OC)C=C6)=C3)=O)=O)=C2)OC([[email protected]@H]7CCCCN7C([[email protected]](C8=CC(OC)=C(OC)C(OC)=C8)CC)=O)=O)C=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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