AP20187

Catalog No.: A21127

AP20187

AP20187 Chemical Structure

CAS NO. 195514-80-8

AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $324.00

Special Price $259.20

5 mg

Regular Price: $972.00

Special Price $777.60

10 mg

Regular Price: $1,656.00

Special Price $1,324.80

50 mg

Regular Price: $4,968.00

Special Price $3,974.40

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Biological Activity

AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.74 mL 33.72 mL 67.44 mL
0.5 mM 1.35 mL 6.74 mL 13.49 mL
1 mM 0.67 mL 3.37 mL 6.74 mL
5 mM 0.13 mL 0.67 mL 1.35 mL

*The above data is based on the productmolecular weight 1482.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21127
CAS No. 195514-80-8
Formula C82H107N5O20
M. Wt 1482.75
Purity >98%
Synonyms B/B Homodimerizer, AP 20187, AP-20187
SMILES COC1=C(OC)C=C(CC[[email protected]](C2=CC=CC(OCC(NCC(CN(C)C)CNC(COC3=CC=CC([[email protected]](OC([[email protected]]4N(C([[email protected]@H](CC)C5=CC(OC)=C(OC)C(OC)=C5)=O)CCCC4)=O)CCC6=CC(OC)=C(OC)C=C6)=C3)=O)=O)=C2)OC([[email protected]@H]7CCCCN7C([[email protected]](C8=CC(OC)=C(OC)C(OC)=C8)CC)=O)=O)C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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