Catalog No.: A14342

GPR119 agonist


APD668 Chemical Structure

CAS NO. 832714-46-2

APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively.

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Biological Activity

APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively.
In vitro DMSO 86 mg/mL (180.1 mM)
Water Insoluble
Ethanol 2 mg/mL (4.18 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.94 mL 104.71 mL 209.42 mL
0.5 mM 4.19 mL 20.94 mL 41.88 mL
1 mM 2.09 mL 10.47 mL 20.94 mL
5 mM 0.42 mL 2.09 mL 4.19 mL

*The above data is based on the productmolecular weight 477.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14342
Actions Agonist
CAS No. 832714-46-2
Formula C21H24FN5O5S
M. Wt 477.51
Purity >98%
Synonyms APD 668, APD-668, JNJ-28630368, JNJ28630368, JNJ 28630368

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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