Aripiprazole (Abilify)

Catalog No.: A11801

5-HT1A receptor agonist

Aripiprazole (Abilify)

Aripiprazole (Abilify) Chemical Structure

CAS NO. 129722-12-9

Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.

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100 mg
$65.00
250 mg
$90.00
500 mg
$115.00
1000 mg
$145.00
10mM * 1mL in DMSO
$50.00
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  • Jaime Osuna-Luque, .et al. Behavioral Mechanisms That Depend on Dopamine and Serotonin in Caenorhabditis elegans Interact With the Antipsychotics Risperidone and Aripiprazole, J Exp Neurosci, 2018, 12: 1179069518798628 PMID: 30245571

Biological Activity

Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.
Targets
5-HT1A
4.2 nM(Ki)
In vitro DMSO 79 mg/mL (176.18 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.51 mL 223.02 mL
0.5 mM 4.46 mL 22.3 mL 44.6 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11801
Actions Agonist
CAS No. 129722-12-9
Formula C23H27Cl2N3O2
M. Wt 448.39
Solubility DMSO
Purity >98%
Synonyms Abilify
SMILES C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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