ARN-3236

Catalog No.: A18725

SIK2 inhibitor

ARN-3236

ARN-3236 Chemical Structure

CAS NO. 1613710-01-2

ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L.

Availability: In stock

Package Price Qty
2 mg
$90.00
5 mg
$130.00
10 mg
$220.00
50 mg
$780.00
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Biological Activity

ARN-3236 is potent, orally active and selective SIK2 inhibitor. ARN-3236 inhibited the growth of 10 ovarian cancer cell lines at an IC50 of 0.8 to 2.6 μmol/L.
In vitro DMSO 62 mg/mL (184.3 mM)
Water Insoluble
Ethanol 2 mg/mL (5.94 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.73 mL 148.63 mL 297.27 mL
0.5 mM 5.95 mL 29.73 mL 59.45 mL
1 mM 2.97 mL 14.86 mL 29.73 mL
5 mM 0.59 mL 2.97 mL 5.95 mL

*The above data is based on the productmolecular weight 336.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18725
Actions Inhibitor
CAS No. 1613710-01-2
Formula C19H16N2O2S
M. Wt 336.4
Solubility DMSO
Purity >98%
Synonyms ARN-3236; ARN 3236; ARN3236.
SMILES COC1=CC=C(C2=CNC3=NC=CC(C4=CSC=C4)=C32)C(OC)=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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