ARRY-380 (Irbinitinib)

Catalog No.: A16413

HER2 inhibitor

ARRY-380 (Irbinitinib) Chemical Structure

CAS NO. 937263-43-9

ARRY-380 is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity.

Availability: In stock

Package Price Qty
5 mg
$65.00
10 mg
$100.00
50 mg
$260.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ARRY-380 is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.81 mL 104.05 mL 208.11 mL
0.5 mM 4.16 mL 20.81 mL 41.62 mL
1 mM 2.08 mL 10.41 mL 20.81 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 480.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16413
Actions Inhibitor
M. Wt 480.52
Formula C26H24N8O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 937263-43-9
Synonyms Tucatinib, ONT-380, Irbinitinib
SMILES CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5

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