ARV-771
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | ARV-771 is a potent BET degrader based on PROTAC technology with Kds of 34, 4.7, 8.3, 7.6, 9.6, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively. | ||
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Targets |
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Catalog Num | A13255 |
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Formula | C49H60ClN9O7S2 |
Molecular Weight | 986.64 |
CAS Number | 1949837-12-0 |
SMILES | CC(C(C(C1=CC=C(Cl)C=C1)=N[C@@H](CC(NCCOCCCOCC(N[C@@H](C(C)(C)C)C(N(C[C@H](O)C2)[C@@H]2C(N[C@H](C3=CC=C(C(SC=N4)=C4C)C=C3)C)=O)=O)=O)=O)C5=NN=C(C)N65)=C6S7)=C7C |
Synonyms | ARV771, ARV 771 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 97 mg/mL (98.31 mM) | |
Water | Insoluble | ||
Ethanol | 97 mg/mL (98.31 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 10.14 mL | 50.68 mL | 101.35 mL |
0.5 mM | 2.03 mL | 10.14 mL | 20.27 mL |
1 mM | 1.01 mL | 5.07 mL | 10.14 mL |
5 mM | 0.2 mL | 1.01 mL | 2.03 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2